Synthesis of piperazine derivatives and evaluation of their antihistamine and antibradykinin effects. |
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Authors: | H Y Choo B J Chung S H Chung |
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Affiliation: | School of Pharmacy, Ewha Womans University, Seoul, Korea. |
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Abstract: | Piperazine derivatives were prepared as histamine antagonists. Some of the synthesized compounds showed dual antagonistic activity against bradykinin as well as histamine. |
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