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Synthesis of piperazine derivatives and evaluation of their antihistamine and antibradykinin effects.
Authors:H Y Choo  B J Chung  S H Chung
Affiliation:School of Pharmacy, Ewha Womans University, Seoul, Korea.
Abstract:Piperazine derivatives were prepared as histamine antagonists. Some of the synthesized compounds showed dual antagonistic activity against bradykinin as well as histamine.
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