Occupational styrene exposure and chromosomal aberrations |
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Authors: | Tytti Meretoja Harri Vainio Marja Sorsa Hannu Härkönen |
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Affiliation: | 1. Department of Industrial Hygiene and Toxicology, Institute of Occupational Health, Finland;1. Department of Genetics, University of Helsinki, Helsinki, Finland |
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Abstract: | Results from a study on the clastogenicity of styrene in vivo are reported. The chromosomes in cultured blood lymphocytes from ten men occupationally exposed to styrene and 5 controls were examined. Styrene-exposed men showed an increase in the rate of chromosomal aberrations. The incidence of aberrant cells ranged from 11 to 26% in the lymphocytes of the exposed subjects and was 3% or less in those of the control group. |
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