Enantioselective Organocatalytic Oxaziridination of N‐Tosyl Aldimine Catalyzed by Cinchona Alkaloid‐Ester Derivatives |
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| Authors: | Ying Jin Tianyi Zhang Wei Zhang Sheng Chang Bo Feng |
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| Institution: | Department of Pharmacy, Jilin Medical College, Jilin, China |
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| Abstract: | A series of cinchona alkaloid‐ester derivatives was synthesized and applied to catalyze the enantioselective oxaziridination of aryl aldimines with m‐CPBA. The (R,R)‐oxaziridines were obtained in good yields with high enantiomeric excess (ee) values (up to 98%). Chirality 26:150–154, 2014. © 2014 Wiley Periodicals, Inc. |
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| Keywords: | cinchona alkaloid‐ester derivatives asymmetric oxaziridination |
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