Behaviour of mouse macrophage cell line and mouse fibroblast on copolymers containing cellulose triacetate. |
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| Authors: | Y Shigemasa H Sashiwa S Tanioka H Saimito T Tanigawa Y Tanaka |
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| Affiliation: | Department of Materials Science, Faculty of Engineering, Tottori University, Japan. |
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| Abstract: | Copolymers containing cellulose triacetate were prepared under various conditions. A bacteriological plastic dish was coated with the copolymer (HCTA-MDI copolymer) composed of hydrolysed cellulose triacetate (HCTA) and diphenylmethane diisocyanate (MDI). The deacetylated copolymer (DA-copolymer) was prepared by the deacetylation of HCTA-MDI copolymer. The behaviour of animal cells such as a mouse macrophage cell line (A640-BB-2 cells) and a mouse fibroblast (3T6 cells) on prepared dishes was investigated morphologically. A640-BB-2 cells showed good adhesion and smooth spreading, and 3T6 cells also showed good adhesion and sufficient cell growth on the dish coated with HCTA-MDI copolymer. These results suggest that these copolymers are useful for biomedical materials. |
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