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Severe hepatopathy in geese and broilers associated with ochratoxin in their feed
Authors:Shlosberg  Alan  Elkin  Nathan  Malkinson  Mertyn  Orgad  Uri  Hanji  Vera  Bogin  Eitan  Weisman  Yoram  Meroz  Michael  Bock  Rachel
Institution:(1) Kimron Veterinary Institute, P.O. Box 12, 50250 Bet Dagan, Israel;(2) Regional Poultry Laboratory, Ra'anana, Israel;(3) Regional Poultry Laboratory, Beer Tuvia, Israel
Abstract:The feeding of a shipment of imported corn was associated with a severe reduction in growth and increased mortality in geese, and increased mortality in broilers. Pathological examinations revealed hepatopathy, visceral gout and mild nephropathy in geese, and in broilers an hepatopathy, which was often severe, and ascites. Samples of feed from affected geese farms were examined for up to 24 mycotoxins, and ochratoxin was found in 6 of 15 samples at levels up to 930 ng/g. The syndrome was experimentally reproduced by feeding geese and broilers suspect feeds with the natural ochratoxin contamination. It is believed that another, unidentified, mycotoxin was the major cause of the hepatotoxicity, and that ochratoxin served in this case as an indicator of a multi-mycotoxin involvement. This revised version was published online in June 2006 with corrections to the Cover Date.
Keywords:Broilers  geese  hepatopathy  mycotoxicosis  nephropathy  ochratoxin
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