Genetic diversity of clinical isolates of <Emphasis Type="Italic">Bacillus cereus</Emphasis>using multilocus sequence typing |
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Authors: | Alex R Hoffmaster Ryan T Novak Chung K Marston Jay E Gee Leta Helsel James M Pruckler Patricia P Wilkins |
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Institution: | (1) National Center for Zoonotic, Vector-borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, USA |
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Abstract: | Background
Bacillus cereus is most commonly associated with foodborne illness (diarrheal and emetic) but is also an opportunistic pathogen that can
cause severe and fatal infections. Several multilocus sequence typing (MLST) schemes have recently been developed to genotype
B. cereus and analysis has suggested a clonal or weakly clonal population structure for B. cereus and its close relatives B. anthracis and B. thuringiensis. In this study we used MLST to determine if B. cereus isolates associated with illnesses of varying severity (e.g., severe, systemic vs. gastrointestinal (GI) illness) were clonal
or formed clonal complexes. |
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Keywords: | |
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