The preparation and properties of a mucopolysaccharide isolated from an ascites mouse tumor |
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| Authors: | WARREN G H HORENSTEIN E GRAY J |
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| Affiliation: | 1. Department of Molecular and Life Sciences, Hanyang University, Ansan, Republic of Korea;2. Institute of Natural Science and Technology, Hanyang University, Ansan, Republic of Korea;3. Department of Bionanotechnology, Hanyang University, Seoul, Republic of Korea;1. Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China;2. School of Public Health, Wannan Medical College, Wuhu, Anhui, China;3. Anhui Province Key Laboratory of Major Autoimmune Diseases, Hefei, Anhui, China;4. Clinic Medical College of Anhui Medical University, Hefei, Anhui, China;1. al-Farabi Kazakh National University, Al-Farabi av. 71, Almaty 050038, Kazakhstan;2. Fessenkov Astrophysical Institute, Observatory 23, Almaty 050020, Kazakhstan |
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| Abstract: | - 1.1. A viscous component of the ascites mouse sarcoma MC1M has been identified as a mucopolysaccharide which is readily attacked by testicular hyaluronidase and appears to be similar to, if not identical with, hyaluronic acid.
- 2.2. Repeated injections of purified hyaluronidase in mice inoculated with sarcoma MC1M failed to show an enhancement of tumor growth. The significance of these results is briefly discussed.
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