Characterization,dissolution and in vivo evaluation of solid acetazolamide complexes |
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| Authors: | Marí a J. Mora,Luis I. Tá rtaraRené e Onnainty,Santiago D. PalmaMarcela R. Longhi,Gladys E. Granero |
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| Affiliation: | Departamento de Farmacia, UNITEFA, CONICET, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, X5000HUA, Argentina |
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| Abstract: | The effects of binary and ternary systems of acetazolamide (ACZ) with hydroxypropyl-β-cyclodextrin (HP-β-CD) alone or with triethanolamine (TEA) on the crystalline properties, dissolution and intraocular pressure (IOP)-lowering effect were investigated. |
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| Keywords: | Hydroxypropyl-β-cyclodextrin Polymorphism Acetazolamide Triethanolamine Freeze-drying |
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