首页 | 本学科首页   官方微博 | 高级检索  
     


Towards understanding structure-stability and surface properties of laminin peptide YIGSR and mutants
Authors:Lakshmanan Muthuselvi  Dhathathreyan Aruna
Affiliation:Chemical Lab., CLRI, Adyar, Chennai 600 020, India.
Abstract:Properties of laminin peptide YIGSR and its mutated sequences YIGSD, YIGSS, YIGSN and YIGSQ have been investigated using molecular dynamics simulations (MDS) and Langmuir films at air/water interface. Simulation studies on laminin peptide YIGSR were performed in the isothermal-isobaric (N, P, T) ensemble, with run up to 5 ns in water as well as lipid environment at 298 K. From different initial configurations, shape transformations of the peptides on the timescale of nanoseconds were observed. The results showed YIGSR to be the most stable peptide with the order of minimized energy being YIGSR
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号