Interaction of Salivary alpha-Amylase and Amylase-Binding-Protein A (AbpA) of <Emphasis Type="Italic">Streptococcus gordonii</Emphasis> with Glucosyltransferase of <Emphasis Type="Italic">S. gordonii</Emphasis> and <Emphasis Type="Italic">Streptococcus mutans</Emphasis> |
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| Authors: | Biswendu Chaudhuri Jennifer Rojek M Margaret Vickerman Jason M Tanzer Frank A Scannapieco |
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| Institution: | (1) Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, New York, USA;(2) Department of Periodontics and Endodontics, School of Dental Medicine, State University of New York at Buffalo, New York, USA;(3) Department of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health Center, Connecticut, USA |
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| Abstract: | Background Glucosyltransferases (Gtfs), enzymes that produce extracellular glucans from dietary sucrose, contribute to dental plaque
formation byStreptococcus gordoniiandStreptococcus mutans. The alpha-amylase-binding protein A (AbpA) ofS. gordonii, an early colonizing bacterium in dental plaque, interacts with salivary amylase and may influence dental plaque formation
by this organism. We examined the interaction of amylase and recombinant AbpA (rAbpA), together with Gtfs ofS. gordoniiandS. mutans. |
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