| 河北省丙型肝炎病毒基因分型研究 |
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| 引用本文： | 牛建章,许若丹,白瑞婷,田茶,张立平,孟宗达.河北省丙型肝炎病毒基因分型研究[J].Virologica Sinica,2003,18(6):611-613. |
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| 作者姓名： | 牛建章 许若丹 白瑞婷 田茶 张立平 孟宗达 |
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| 作者单位： | [1]河北大学生命科学学院，河北保定，071002 [2]河北省疾病预防控制中心，河北石家庄050011 |
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| 基金项目： | 河北省医学重点跟踪项目(99037) |
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| 摘 要： | Using nested RT-PCR and type special primers of HCV, we performed genotype analysis of HCV RNA from five representative cities in Hebei Province. Among 168 samples with HCV RNA, 104 sera was typelb(61.9%), type 2a account for 22.6% (38/168) , and lb/2a mixed-type was 15.5% (26/168) . The results indicate that typelb is the dominance strain in Hebei Province. Compared with type 2a, typelb has important relationship with chronic hepatitis C. This study build up some foundations for diagnosis, treatment and vaccine study of hepatitis C.
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| 关 键 词： | 丙型肝炎病毒 基因分型 巢式RT—PcR 基因序列 |
Genotyping of Hepatitis C Virus in Hebei Province |
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| NIU Jian-zhang.Genotyping of Hepatitis C Virus in Hebei Province[J].中国病毒学(英文版),2003,18(6):611-613. |
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| Authors: | NIU Jian-zhang |
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| Institution: | NIU Jian-zhang~ |
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| Abstract: | Using nested RT-PCR and type special primers of HCV, we performed genotype analysis of HCV RNA from five representative cities in Hebei Province. Among 168 samples with HCV RNA, 104 sera was typelb(61.9%), type 2a account for 22.6% (38/168) , and Ib/2a mixed-type was 15.5% (26/168) . The results indicate that typelb is the dominance strain in Hebei Province. Compared with type 2a, typelb has important relationship with chronic hepatitis C. This study build up some foundations for diagnosis, treatment and vaccine study of hepatitis C. |
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| Keywords: | Hepatitis C virus(HCV) Genotyping Nested RT-PCR |
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