Diabetes-induced variation in hepatic binding protein |
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| Authors: | M Dodeur S Coumoul D Durand G Durand J Feger J Agneray |
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| Affiliation: | Cetus Corporation, 1400 Fifty-Third Street, Emeryville, CA 94608 USA |
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| Abstract: | The total capacity of hepatocytes to bind asialoorosomucoid was measured on normal and streptozotocin diabetic rats. 4 days after the streptozotocin injection, a slight decrease of total receptor concentration was observed while a more marked reduction of cell surface receptor occurred. In animals sacrificed 11 days after the streptozotocin injection, the total capacity of hepatocytes to bind asialoorosomucoid was about 70% of the normal level. |
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| Keywords: | To whom correspondence should be addressed. |
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