CytReD: A database collecting human cytokinome information |
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| Authors: | Miele Marco Sharma Ankush Capone Francesca Raucci Raffaele Guerriero Eliana Colonna Giovanni Castello Giuseppe Stasio Michele Di Costantini Susan |
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| Affiliation: | 1INT Pascale - CROM, via Ammiraglio Bianco, 83013 Mercogliano (IT);2Department of Biochemistry and Biophysics and CRISCEB - (Interdepartmental Research Center for Computational and Biotechnological Sciences), Second University of Naples, via Costantinopoli 16, 80138 Naples (IT);3Institute of Food Sciences -CNR Via Roma, 64 83100 – Avellino (IT) |
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| Abstract: | The cytokines/related receptors system represents a complex regulatory network that is involved in those chronic inflammatory processes which lead to many diseases as cancers. We developed a Cytokine Receptor Database (CytReD) to collect information on cytokine receptors related to their biological activity, gene data, protein structures and diseases in which these and their ligands are implicated. This large set of information may be used by researchers as well as by physicians or clinicians to identify which cytokines, reported in the literature, are important in a given disease and, therefore, useful for purposes of diagnosis or prognostic. AVAILABILITY: The database is available for free at http://www.cro-m.eu/CytReD/ |
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