|
|||||
|
|
Perindopril and ramipril phosphonate analogues as a new class of angiotensin converting enzyme inhibitors |
|
| Authors: | Catherine Gomez Sabine Berteina-Raboin Guillaume De Nanteuil Gérald Guillaumet |
| Affiliation: | 1. Institut de Chimie Organique et Analytique, Université d’Orléans, UMR CNRS 7311, rue de Chartres, BP 6759, 45067 Orléans Cedex 2, France;2. Institut de Recherche Servier, 125 chemin de Ronde, 78290 Croissy sur Seine, France |
| Abstract: | A series of phosphonate analogues related to perindopril and ramipril were prepared and tested to estimate their ability to inhibit angiotensin converting enzyme. These new synthesized compounds were active ACE inhibitors with a promising activity. |
| Keywords: | Phosphonate Inhibitors Angiotensin converting enzyme Hypertension |
| 本文献已被 ScienceDirect 等数据库收录！ | |