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Protein-Peptide Complex Prediction through Fragment Interaction Patterns

Authors:	Erik Verschueren Peter Vanhee Frederic Rousseau Joost Schymkowitz Luis Serrano

Institution:	1. EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, 08003 Barcelona, Spain;2. Universitat Pompeu Fabra (UPF), Dr. Aiguader 88, 08003 Barcelona, Spain;3. Institució Catalana de Recerca i Estudis Avançats (ICREA), Pg. Lluis Companys 23, 08010 Barcelona, Spain;4. Switch Laboratory, VIB, 3000 Leuven, Belgium;5. Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium

Abstract:	Download : Download high-res image (255KB) Download : Download full-size image Highlights? Polypeptide fragment interaction patterns predict bound protein-peptide complexes ? Peptide structures can be refined or extended by polypeptide fragment alphabets ? Interacting polypeptide fragment pairs guide domain-domain interface identification ? Interacting polypeptide fragment scaffolds have potential to dock protein domains

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