1. Department of Biochemistry and Molecular Biology, Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
Abstract:
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Highlights? Autoinhibitory regions in proteins are enriched in intrinsic disorder ? Modulation of intrinsic disorder contributes to the fine-tuning of autoinhibition ? Disordered autoinhibitory regions are more often phosphorylated and change structure ? Intrinsic disorder in inhibitory regions is exploited to fine-tune inhibition
