1. Laboratory of Cellular and Molecular Neurophysiology, Porter Neuroscience Research Center, NICHD, NIH, DHHS, Bethesda, MD 20892, USA;2. Bioengineering and Physical Science Shared Resource, NIBIB, NIH, DHHS, Bethesda, MD 20892, USA
Abstract:
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Highlights? The AvGluR1 LBD is a hybrid structure with iGluR prokaryotic and eukaryotic features ? AvGluR1 binds hydrophobic amino acids as well as glutamate ? Chloride ions acts as surrogate ligand atoms in the Ala, Ser, and Met complexes ? The AvGluR1 LBD assembles as a dimer but with very low affinity
