|
|||||
|
|
Synthesis and anti-inflammatory activity of aromatic glucosinolates |
|
| Authors: | Quan V. Vo Craige Trenerry Simone Rochfort Jenny Wadeson Carolina Leyton Andrew B. Hughes |
| Affiliation: | 1. Department of Chemistry, La Trobe University, Victoria 3086, Australia;2. Department of Primary Industries, Knoxfield Centre, 621 Burwood Highway, Knoxfield 3180, Australia;3. Department of Primary Industries, Victorian AgriBiosciences Centre, La Trobe University Research and Development Park, 1 Park Drive, Bundoora 3083, Victoria, Australia;4. La Trobe University, Victoria 3086, Australia |
| Abstract: | Aromatic GLs are important members of the glucosinolate family of compounds because of their potential biological activity and medicinal properties. This study has shown success in the high yielding synthesis of some important aromatic GLs as well as the results of testing for anti-inflammatory properties of the synthetic GLs. 3,4-Dimethoxyphenylglucosinolate was found to be the most active anti-inflammatory of the seven glucosinolates assayed. |
| Keywords: | Aromatic glucosinolate Anti-inflammatory TNFalpha 3,4-Dimethoxyphenylglucosinolate |
| 本文献已被 ScienceDirect 等数据库收录！ | |