蛋白质折迭的不可逆热力学理论及蛋白质动态热力学结构(英)

在机械力学及热力学基础上阐述蛋白质的各种物理性质是从物理学角度理解生物学的基础性工作.详细讨论了蛋白质折迭的不可逆热力学理论，蛋白质动态热力学结构理论.理论推断蛋白质动态热力学变化是一切生物学状态变化的基本热力学状态单位并作为分子生物学变化的分子开关.利用此理论解释了蛋白质的物理学性质及麻醉药的生物物理学机制.

Irreversible Thermodynamic Theory for Protein Folding and Protein ThermodynamicStructures

The interpretation of protein physical properties at the most fundamental mechanistic and thermodynamic level plays a key role in physical and molecular understanding of biology. The protein thermodynamic structure (potherse) is generated through irreversible thermodynamic possesses. Protein folding is a specific physical mechanism for the origin of natural order. It was shown that pothersal change is the basic (molecular) thermodynamic unit of any physiological reaction which acts as a molecular switch. The Weiss equation is re-derived using protein mechanics theory. Some protein physical properties are also discussed.