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Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2–ARE pathways in cell models of spinocerebellar ataxia 3
Institution:1. Department of Neurology, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taipei 10507, Taiwan;2. Department of Life Science, National Taiwan Normal University, 88 Ting-Chou Road, Section 4, Taipei 11677, Taiwan;3. Center of Excellence for Drug Development, Industrial Technology Research Institute, Hsinchu 31040, Taiwan;4. Center of Excellence for Diagnostic Products, Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 31040, Taiwan
Abstract:
Keywords:Spinocerebellar ataxia  ATXN3  Licochalcone A  Ammonium glycyrrhizinate  PPARGC1A  NFE2L2  Mitochondrial biogenesis  Oxidative stress  Free radicals
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