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Arctigenin,a dietary phytoestrogen,induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation
Institution:1. University Hospital Basel, Department of Biomedicine, Basel, Switzerland;2. Novartis Institutes for Biomedical Research, Department of Discovery and Investigative Safety, Basel, Switzerland;1. Wuhan Institute of Animal Husbandry and Veterinary Science, Wuhan Academy of Agricultural Science & Technology, Wuhan 430208, Hubei, People''s Republic of China;2. College of Veterinary Medicine, China Agricultural University, Beijing, People''s Republic of China;3. State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People''s Republic of China
Abstract:
Keywords:Arctigenin  Phytoestrogen  Apoptosis  Oxidative stress  Epigenetic  Breast cancer  Free radicals
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