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Simultaneous detection of multiple single-base alleles at a polymorphic site. |
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| Authors: | C Dutton S S Sommer |
| Affiliation: | Department of Biochemistry and Molecular Biology, Mayo Clinic/Foundation, Rochester, MN 55905. |
| Abstract: | PCR amplification of multiple specific alleles (PAMSA) is a rapid method of detecting single-base polymorphisms. We demonstrate its utility by detecting a polymorphism in an Alu sequence in the factor IX gene. |
| Keywords: | |