Discrimination of suppressor T cells of humoral and cell-mediated immunity by anti-Ly and anti-Ia sera. |
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| Authors: | I A Ramshaw I F McKenzie P A Bretscher C R Parish |
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| Affiliation: | 1. Department of Microbiology, John Curtin School of Medical Research, Australian National University, Canberra, Australia;2. Department of Medicine, Austin Hospital, Heidelberg, Victoria, Australia |
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| Abstract: | Evidence is presented which demonstrates that the T lymphocytes which suppress humoral and cell-mediated immunity in CBA/H mice differ in the cell surface structures they express. The suppressor T cells of delayed-type hypersensitivity are Ly-1+, Ly-2? and Ia?, whereas the suppressor T cells of antibody formation are Ly-1?, Ly-2+ and Ia+. |
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