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Novel induced <Emphasis Type="Italic">mlo</Emphasis> mutant alleles in combination with site-directed mutagenesis reveal functionally important domains in the heptahelical barley Mlo protein |
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| Authors: | Anja Reinstädler Judith Müller Jerzy H Czembor Pietro Piffanelli Ralph Panstruga |
| Institution: | 1.Max-Planck Institute for Plant Breeding Research,Department of Plant-Microbe Interactions,K?ln,Germany;2.Ulm University,Department for Molecular Genetics and Cell Biology,Ulm,Germany;3.Plant Breeding and Acclimatization Institute (IHAR),Plant Breeding and Genetics Department,Radzikow,Poland;4.The Sainsbury Laboratory,John Innes Centre,Norwich,UK;5.Parco Tecnologico Padano,Località Cascina Codazza,Italy |
| Abstract: | BackgroundRecessively inherited natural and induced mutations in the barley Mlo gene confer durable broad-spectrum resistance against the powdery mildew pathogen, Blumeria graminis f.sp. hordei. Mlo codes for a member of a plant-specific family of polytopic integral membrane proteins with unknown biochemical activity. Resistant barley mlo mutant alleles identify amino acid residues that are critical for Mlo function in the context of powdery mildew susceptibility. |
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