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The proline-rich peptide Bac7(1-35) reduces mortality from <Emphasis Type="Italic">Salmonella typhimurium</Emphasis> in a mouse model of infection |
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| Authors: | Monica Benincasa Chiara Pelillo Sonia Zorzet Chiara Garrovo Stefania Biffi Renato Gennaro Marco Scocchi |
| Institution: | (1) Department of Life Sciences, University of Trieste, Via Giorgieri 1, 34127 Trieste, Italy;(2) Optical Imaging Laboratory, CBM, Area Science Park, Trieste, Italy |
| Abstract: | BackgroundBac7 is a proline-rich peptide with a potent in vitro antimicrobial activity against Gram-negative bacteria. Here we investigated its activity in biological fluids and in vivo using a mouse model of S. typhimurium infection. |
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