Cytotoxic Polyphenols from a Sponge‐Associated Fungus Aspergillus versicolor Hmp‐48 |
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Authors: | Xiao Wang Yanhua Mou Jiangchun Hu Nan Wang Li Zhao Li Liu Shujin Wang Dali Meng |
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Institution: | 1. Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, P.?R. China, (phone: +86‐88087740);2. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China;3. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China |
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Abstract: | A new dibenzo1,4]dioxin 1 , and two new prenylated diphenyl ethers, 2 and 3 , together with six known compounds, 4 – 9 , were isolated from a sponge‐associated fungus Aspergillus versicolor Hmp‐F48 by bioactivity‐guided fractionation. Their structures were elucidated by 1D‐ and 2D‐NMR, and MS analyses. The compounds showed potent cell growth inhibitory activities against HL‐60 cell line. |
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Keywords: | Aspergillus versicolor Sponges Fungus Dibenzo[1 4]dioxin |
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