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Cytotoxic Polyphenols from a Sponge‐Associated Fungus Aspergillus versicolor Hmp‐48
Authors:Xiao Wang  Yanhua Mou  Jiangchun Hu  Nan Wang  Li Zhao  Li Liu  Shujin Wang  Dali Meng
Institution:1. Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, P.?R. China, (phone: +86‐88087740);2. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China;3. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China
Abstract:A new dibenzo1,4]dioxin 1 , and two new prenylated diphenyl ethers, 2 and 3 , together with six known compounds, 4 – 9 , were isolated from a sponge‐associated fungus Aspergillus versicolor Hmp‐F48 by bioactivity‐guided fractionation. Their structures were elucidated by 1D‐ and 2D‐NMR, and MS analyses. The compounds showed potent cell growth inhibitory activities against HL‐60 cell line.
Keywords:Aspergillus versicolor  Sponges  Fungus  Dibenzo[1  4]dioxin
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