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New Triterpenoids from the Fruiting Bodies of Ganoderma lucidum and Their Bioactivities
Authors:Dong‐Ze Liu  Yi‐Qun Zhu  Xiao‐Fei Li  Wei‐Gang Shan  Peng‐Fei Gao
Institution:1. Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, P.?R. China;2. Sichuan Agricultural University, Yaan 625014, P.?R. China
Abstract:Phytochemical investigation of the AcOEt extract of G. Lucidum has led to the isolation of two new triterpenoids, 1 and 2 , together with five known ones, 3 – 7 . The structures of the new compounds were identified as 12β‐acetoxy‐3β,7β‐dihydroxy‐11,15,23‐trioxolanost‐8‐en‐26‐oic acid butyl ester ( 1 ) and 12β‐acetoxy‐3,7,11,15,23‐pentaoxolanost‐8‐en‐26‐oic acid butyl ester ( 2 ) on the basis of detailed spectroscopic analysis (mass spectrometry, and 1D‐ and 2D‐NMR experiments). The antimicrobial activities of 1 and 2 were also evaluated.
Keywords:Triterpenoids  Lanostane  Ganoderma lucidum  Fungi  Antimicrobial activity
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