New Triterpenoids from the Fruiting Bodies of Ganoderma lucidum and Their Bioactivities |
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Authors: | Dong‐Ze Liu Yi‐Qun Zhu Xiao‐Fei Li Wei‐Gang Shan Peng‐Fei Gao |
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Institution: | 1. Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, P.?R. China;2. Sichuan Agricultural University, Yaan 625014, P.?R. China |
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Abstract: | Phytochemical investigation of the AcOEt extract of G. Lucidum has led to the isolation of two new triterpenoids, 1 and 2 , together with five known ones, 3 – 7 . The structures of the new compounds were identified as 12β‐acetoxy‐3β,7β‐dihydroxy‐11,15,23‐trioxolanost‐8‐en‐26‐oic acid butyl ester ( 1 ) and 12β‐acetoxy‐3,7,11,15,23‐pentaoxolanost‐8‐en‐26‐oic acid butyl ester ( 2 ) on the basis of detailed spectroscopic analysis (mass spectrometry, and 1D‐ and 2D‐NMR experiments). The antimicrobial activities of 1 and 2 were also evaluated. |
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Keywords: | Triterpenoids Lanostane Ganoderma lucidum Fungi Antimicrobial activity |
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