Altered regulation of pancreatic glucagon in male rats during aging. |
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Authors: | T L Klug C Freeman K Karoly R C Adelman |
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Affiliation: | Bell Laboratories Murray Hill, New Jersey 07974 USA;Kent State University Kent, Ohio 44242 USA |
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Abstract: | Using x-ray diffraction, the interaction of calcium ions with dipalmitoyl phosphatidylcholine (DPPC) multilayers in excess solution has been studied as a function of temperature over a range of concentrations. We have discovered order-disorder-order transformations as a function of both increasing temperature and calcium concentration. For pure DPPC, the pretransition is characterized by a large increase in lattice disorder. For low calcium concentrations, a similar increase in lattice distortion occurs for all temperatures. The high temperature phase is marked by a significant reduction in this disorder. Likewise ordering of the multilayer is regained at high calcium concentrations. |
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Keywords: | To whom inquiries should be addressed at the Temple University Institute on Aging 3400 N. Broad Street Philadelphia PA 19140. |
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