益生菌对不同年龄人群功能性便秘治疗效果的研究进展

功能性便秘是一种常见的功能性胃肠道疾病。患者通常伴有腹痛、腹胀等现象,严重影响患者生活质量,其治疗仍具有挑战性。近年来研究发现肠道菌群紊乱与功能性便秘的发生发展密切相关。益生菌能够调节肠道菌群平衡,加强肠道生物的屏障功能,参与免疫系统发挥作用,为治疗功能性便秘提供了新思路。本文对益生菌治疗功能性便秘的现状进行综述,阐明功能性便秘的发生机制、功能性便秘患者的肠道菌群变化及益生菌治疗不同年龄人群功能性便秘的效果,为益生菌在功能性便秘患者中的应用提供参考。

Probiotics in the treatment of functional constipation in different age groups:research progress

Functional constipation is a common functional gastrointestinal disease. The patients usually have symptoms such as abdominal pain, abdominal distension and other phenomena, which seriously affect their quality of life. The treatment of the disease remains a challenge. Recent research has found that intestinal flora disorder is closely related to the occurrence and development of functional constipation. Probiotics can regulate the balance of intestinal flora, strengthen the barrier function of intestinal organisms and play a role in the immune system, which provides a new idea for treatment. This paper will review the present status of probiotics in the treatment of functional constipation, and discuss the mechanism of functional constipation, the changes of intestinal flora in patients and the effect of probiotics in the treatment of functional constipation in people at different ages. The purpose is to provide reference for the application of probiotics in patients with functional constipation.