Identification of meso-hydroxyuroporphyrin I in the urine of a patient with congenital erythropoietic porphyria. |
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| Authors: | R Guo J M Rideout C K Lim |
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| Affiliation: | Division of Clinical Cell Biology, M.R.C. Clinical Research Centre, Harrow, Middx., U.K. |
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| Abstract: | A new porphyrin, meso-hydroxyuroporphyrin I, was isolated from the urine of a patient with congenital erythropoietic porphyria. The structure was characterized as the methyl ester, ethyl ester and acetoxy derivatives by fast-atom-bombardment m.s., by conversion into uroporphyrin I and by chemical synthesis. |
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