Evidence that In Vitro Susceptibility of CD3+ T Lymphocytes to Equine Arteritis Virus Infection Reflects Genetic Predisposition of Naturally Infected Stallions To Become Carriers of the Virus |
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| Authors: | Yun Young Go Ernest Bailey Peter J Timoney Kathleen M Shuck Udeni B R Balasuriya |
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| Institution: | Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, Kentucky, USA |
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| Abstract: | We investigated the correlation between in vitro susceptibility of CD3+ T lymphocytes to equine arteritis virus (EAV) infection and establishment of persistent infection among 14 stallions following natural infections. The data showed that carrier stallions with a CD3+ T lymphocyte susceptibility phenotype to in vitro EAV infection may be at higher risk of becoming carriers than those that lack this phenotype (P = 0.0002). |
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