Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation |
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Authors: | Nancy Maizels |
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Affiliation: | (1) Departments of Immunology and Biochemistry, University of Washington Medical School, 1959 NE Pacific Street, Seattle, WA 98195-7650, USA |
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Abstract: | A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between these two processes. |
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