Ethionine and Methionine Metabolism by the Chrysomonad Flagellate Prymnesium parvum |
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Authors: | M. RAHAT A. HOCHBERG |
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Affiliation: | Depts. of Zoology and of Organic and Biological Chemistry, Hebrew Univ., Jerusalem, Israel |
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Abstract: | SYNOPSIS. Ethionine or methionine can serve as sole nitrogen source for growth of Prymnesium parvum. Both amino acids are taken up as such at a ratio of 2 : 1 methionine/ethionine. Ethionine is totally de-ethylated in the cell, while methionine is probably only partially de-methylated. The homocysteine moiety of both amino acids is similarly metabolised to form cysteine or re-methylated to form methionine. De-ethylation of ethionine seems how P. parvum avoids its antimetabolic effect |
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