Isolation and Partial Characterization of a Temperature-Sensitive Escherichia coli Mutant with Altered Glutaminyl-Transfer Ribonucleic Acid Synthetase |
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Authors: | A. K rner, B. B. Magee, B. Liska, K. B. Low, E. A. Adelberg, D. S ll |
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Affiliation: | A. Körner, B. B. Magee, B. Liska, K. B. Low, E. A. Adelberg, and D. Söll |
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Abstract: | A temperature-sensitive mutant of Escherichia coli has been found in which the conditional growth is a result of a thermosensitive glutaminyl-transfer ribonucleic acid synthetase. The corresponding genetic locus glnS is cotransduced with lip. In a strain containing the mutationally altered glutaminyl-transfer ribonucleic acid synthetase, no derepression of the enzyme itself nor of glutamine synthetase was observed. |
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