Distance measurements via the morphogen gradient of Bicoid in <Emphasis Type="Italic">Drosophila</Emphasis> embryos期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Distance measurements via the morphogen gradient of Bicoid in <Emphasis Type="Italic">Drosophila</Emphasis> embryos

Authors:	Feng He Ying Wen David Cheung Jingyuan Deng Long J Lu Renjie Jiao Jun Ma

Institution:	(1) State Key Laboratory of Brain and Cognitive Science Institute of Biophysics Chinese Academy of Sciences, 15 Datun Road, Beijing, 100101, China;(2) Graduate School of the Chinese Academy of Sciences, Beijing, 100049, China;(3) Divisions of Biomedical Informatics Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA;(4) Developmental Biology Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA;(5) Department of Biomedical Engineering, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45221, USA

Abstract:	Background Patterning along the anterior-posterior (A-P) axis in Drosophila embryos is instructed by the morphogen gradient of Bicoid (Bcd). Despite extensive studies of this morphogen, how embryo geometry may affect gradient formation and target responses has not been investigated experimentally.

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