Condensation reaction of hexanucleotides containing guanine and cytosine with water soluble carbodiimide. |
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| Authors: | K Kawamura F Okamoto |
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| Institution: | Department of Applied Chemistry, College of Engineering, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan. |
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| Abstract: | The condensation reactions of hexanucleotides involving guanine and cytosine in the presence of water-soluble carbodiimide (WSC) have been investigated as a model reaction of the prebiotic formation of RNA under primitive earth. The reactions formed cyclic hexanucleotides and dimers in which the product yields were dependent on the sequence. |
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