A Novel Erythromycin Resistance Plasmid from Bacillus Sp. Strain HS24, Isolated from the Marine Sponge Haliclona Simulans
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| Authors: | Teresa M Barbosa Robert W Phelan Dara Leong John P Morrissey Claire Adams Alan D W Dobson Fergal O’Gara |
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| Institution: | 1. School of Pharmacy, University College Cork, Cork, Ireland.; 2. Department of Microbiology, University College Cork, Cork, Ireland.; 3. Biomerit Research Centre, University College Cork, Cork, Ireland.; 4. Marine Biotechnology Centre, Environmental Research Institute, University College Cork, Cork, Ireland.; 5. Curtin University, School of Biomedical Sciences, Perth WA 6845, Australia.; Catalan Institute for Water Research (ICRA), Spain, |
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| Abstract: | A better understanding of the origin and natural reservoirs of resistance determinants is fundamental to efficiently tackle antibiotic resistance. This paper reports the identification of a novel 5.8 kb erythromycin resistance plasmid, from Bacillus sp. HS24 isolated from the marine sponge Haliclona simulans. pBHS24B has a mosaic structure and carries the erythromycin resistance gene erm(T). This is the first report of an erythromycin resistance plasmid from a sponge associated bacteria and of the Erm(T) determinant in the genus Bacillus. |
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