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Organizing knowledge to enable personalization of medicine in cancer |
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| Authors: | Benjamin M Good Benjamin J Ainscough Josh F McMichael Andrew I Su Obi L Griffith |
| Affiliation: | .Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 USA ;.The Genome Institute, Washington University School of Medicine, 4444 Forest Park Ave, St Louis, MO 63108 USA ;.Department of Genetics, Washington University School of Medicine, 660 S. Euclid Ave, St Louis, MO 63110 USA ;.Department of Medicine, Washington University School of Medicine, 660 S. Euclid Ave, St Louis, MO 63110 USA |
| Abstract: | Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer. |
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