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Reserpine Is the New Addition into the Repertoire of AcrB Efflux Pump Inhibitors
Authors:Shaheen  A.  Afridi  W. A.  Mahboob  S.  Sana  M.  Zeeshan  N.  Ismat  F.  Mirza  O.  Iqbal  M.  Rahman  M.
Affiliation:1.Drug Discovery and Structural Biology group, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering (NIBGE), 44000, Faisalabad, Pakistan
;2.Department of Biochemistry and Biotechnology, University of Gujrat, Hafiz Hayat Campus, 50700, Gujrat, Pakistan
;3.Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences,University of Copenhagen, 1165, Copenhagen, Denmark
;
Abstract:Molecular Biology - Acriflavine resistance protein B (AcrB) serves as prototype for multidrug resistance (MDR) efflux transporters of resistance nodulation division (RND) superfamily. AcrB has been...
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