Synchrony in telomere length of the human fetus |
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| Authors: | Kjell Youngren Elisabeth Jeanclos Hana Aviv Masayuki Kimura Jeffrey Stock Moneer Hanna J Skurnick Arlene Bardeguez A Aviv |
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| Institution: | (1) Division of Urology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA, US;(2) Hypertension Research Center, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA e-mail: avivab@umdnj.edu, Tel.: +1 973 972 5280, Fax: +1 973 972-5576, US;(3) Center for Human and Molecular Genetics, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA, US;(4) Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA, US |
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| Abstract: | Telomere length, measured by terminal restriction fragments, was examined in tissues from human fetuses of gestational ages
estimated as 15–19 weeks. The length of telomeres was similar in most fetal tissues. However, there were significant variations
in telomere length among fetuses, with no apparent relationship between gestational age and telomere length. We conclude that
synchrony in telomere length exists among tissues of the human fetus. This synchrony is apparently lost during extrauterine
life.
Received: 12 January 1998 / Accepted: 19 March 1998 |
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