Cardiac Troponin I in Non- Acute Coronary Syndrome Patients with Chronic Kidney Disease |
| |
Authors: | Shanying Chen Chunhong Huang Bide Wu Xuejian Lian Xuqiao Mei Jianxin Wan |
| |
Affiliation: | 1. Department of Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.; 2. Clinical Laboratory, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.; 3. Department of Nephrology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China .; S.G.Battista Hospital, Italy, |
| |
Abstract: | ObjectiveThe aim of this study was to assess the results of troponin I (cTnI) in non- acute Coronary Syndrome (ACS) patients with chronic kidney disease (CKD). We also examined the risk factors for elevated cTnI in non-ACS patients with CKD and whether stage 5 CKD modifies the associations of elevated cTnI and the risk factors in non-ACS patients with CKD.MethodsA retrospective study was performed. Logistic regression models were used.Results293 non-ACS patients with CKD were included in the current study. 43.34% non-ACS patients with CKD have an elevated cTnI level and 5.12% have an elevated cTnT level in MI range. In CKD patients without ACS and heart failure, only 26.03% (38/146) patients have an elevated cTnT level. In adjusted analyses, age, diastolic blood pressure and congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD (OR 2.30, 95% CI 1.08,4.88, P=0.03). Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level.Conclusion43.34% non-ACS patients with CKD and 26.03% CKD patients without ACS and congestive heart failure have an elevated cTnI level. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level. |
| |
Keywords: | |
|
|