Calcitonin and secretin inhibit bombesin-stimulated serum gastrin and gastric acid secretion in man |
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Authors: | JBMJ Jansen CBHW Lamers |
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Institution: | Division of Gastroenterology, Department of Medicine, St. Radboud Hospital, University of Nijmegen, Nijmegen, The Netherlands |
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Abstract: | The effect of intravenously administered calcitonin and secretin on bombesin-stimulated serum gastrin and gastric acid secretion was studied in 7 volunteers. Secretin G.I.H. (1 C.U./kg per h) and calcitonin (0.5 I.U./kg per h) significantly () inhibited the serum gastrin and gastric acid responses to bombesin-14 (90 pmol/kg per h). Inhibition of gastrin release could not fully account for the inhibition of gastric acid secretion. |
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Keywords: | bombesin calcitonin secretin gastrin gastric acid |
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