Conservation implications of limited genetic diversity and population structure in Tasmanian devils (Sarcophilus harrisii) |
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Authors: | Sarah Hendricks author-information" >,Brendan Epstein,Barbara Schönfeld,Cody Wiench,Rodrigo Hamede,Menna Jones,Andrew Storfer,Paul Hohenlohe |
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Affiliation: | 1.Department of Biological Sciences, Institute for Bioinformatics and Evolutionary Studies,University of Idaho,Moscow,USA;2.School of Biological Sciences,Washington State University,Pullman,USA;3.School of Biological Sciences,University of Tasmania,Hobart,Australia |
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Abstract: | Tasmanian devils face a combination of threats to persistence, including devil facial tumor disease (DFTD), an epidemic transmissible cancer. We used RAD sequencing to investigate genome-wide patterns of genetic diversity and geographic population structure. Consistent with previous results, we found very low genetic diversity in the species as a whole, and we detected two broad genetic clusters occupying the northwestern portion of the range, and the central and eastern portions. However, these two groups overlap across a broad geographic area, and differentiation between them is modest (({{F}_{text{ST}}})?=?0.1081). Our results refine the geographic extent of the zone of mixed ancestry and substructure within it, potentially informing management of genetic variation that existed in pre-diseased populations of the species. DFTD has spread across both genetic clusters, but recent evidence points to a genomic response to selection imposed by DFTD. Any allelic variation for resistance to DFTD may be able to spread across the devil population under selection by DFTD, and/or be present as standing variation in both genetic regions. |
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