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Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps
Affiliation:1. Laboratory of Intestinal Immunology, Department of Immunology and Pathology, Monash University, Melbourne, VIC 3004, Australia;2. Laboratory of Intestinal Immunology, SV, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne CH-1015 Switzerland;3. Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD 4814, Australia;4. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid 28222, Spain;5. Antimicrobial Defense Laboratory, The Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK;6. Bioimaging and Optics Core Facility, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne CH-1015, Switzerland;7. Malaghan Institute of Medical Research, Wellington 6242, New Zealand;8. Hugh Green Cytometry Centre, Malaghan Institute of Medical Research, Wellington 6242, New Zealand
Abstract:
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  • Keywords:neutrophils  neutrophil extracellular traps  DNAse II  hookworm  Nippostrongylus brasiliensis  helminth  immune-evasion
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