Improved reproducibility of citric acid production in Aspergillus niger |
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| Authors: | Renato Bonatelli Junior João Lúcio De Azevedo |
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| Affiliation: | (1) Department of Genetics and Evolution, IB - Unicamp, P.O. Box 1170, 13100 Campinas, SP, Brasil;(2) Laboratory of Genetics, Department of Animal Biology, University of Brasilia, 79100 Brasília, Df, Brasil |
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| Abstract: | Summary We report the derivation of Aspergillus niger strains having a lower standard deviation in citric acid production by the use of 60Co gamma radiation and by the parasexual cycle. On the basis of the results obtained by isolating diploids and segregants, diploidization seems to be sufficient for reducing variability. The implications of these results in terms of improvement of industrial strains are discussed. |
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