Lewis a blood group antigen of non-secretors: a receptor for candida blastospores |
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| Authors: | S J May C C Blackwell D M Weir |
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| Affiliation: | Department of Bacteriology, Medical School, University of Edinburgh, U.K. |
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| Abstract: | This study tested the hypothesis that the Lewis a blood group antigen found predominantly on the cells of non-secretors might be one of the receptors for Candida species. Binding of strain 3118C to epithelial cells from either secretor or non-secretor donors was not inhibited by treating the cells with anti-Lewis a or anti-Lewis b antisera. Binding of strain 3091 to non-secretor cells was inhibited by pretreating the cells with anti-Lewis a, but this was not observed for secretor cells. The results suggest that Lewis a might be one of the receptors for some yeast strains. |
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