Chromosome segregation: keeping kinetochores in the loop |
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| Authors: | Schmidt Jens C Cheeseman Iain M |
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| Affiliation: | Whitehead Institute for Biomedical Research, and Department of Biology, Massachusetts Institute of Technology, Nine Cambridge Center, Cambridge, MA 02142, USA |
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| Abstract: | The Ndc80 complex is a key component of the kinetochore-microtubule interface. Two studies now demonstrate that a conserved loop region within the extended coiled-coil of Ndc80 plays an unexpected role in recruiting proteins to the kinetochore. |
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