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Mitochondrial dynamics: a strategy for avoiding autophagy |
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| Authors: | Galluzzi Lorenzo Kepp Oliver Kroemer Guido |
| Affiliation: | 1 INSERM, U848 “Apoptosis, Cancer and Immunity”, F-94805 Villejuif, France 2 Institut Gustave Roussy, F-94805 Villejuif, France 3 Université Paris Sud-XI, F-94805 Villejuif, France 4 Metabolomics Platform, Institut Gustave Roussy, F-94805 Villejuif, France 5 Centre de Recherche des Cordoliers, F-75005 Paris, France 6 Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, F-75908 Paris, France 7 Université Paris Descartes, Paris 5, F-75270 Paris, France |
| Abstract: | Cells normally respond to a lack of nutrients by activating autophagy, a prominent pro-survival pathway that involves the catabolism and recycling of cytoplasmic material. Recent results indicate that mitochondria actively elongate during autophagy, thereby avoiding their degradation and sustaining cell viability. |
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