Synaptic growth: dancing with adducin |
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Authors: | Stevens Robin J Littleton J Troy |
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Institution: | The Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA |
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Abstract: | Manipulations of the actin-capping protein adducin in Drosophila and mammalian neurons provide new insights into the mechanisms linking structural changes to synaptic plasticity and learning. Adducin regulates synaptic remodeling, providing a molecular switch that controls synaptic growth versus disassembly during plasticity. |
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