Abstract: | It was found that neuronal activity of the rabbit somatosensory cortex could be operantly conditioned according to the given algorithm of biofeedback control of nociceptive stimulation leading to rising or lowering of firing rate of multiunit activity, or to changes of range of units interspike intervals, or neuronal firing patterns for conditional stimulus, which become operants. Neuronal interactions of its population with feedback and systems of cardiovascular and pain regulation lead to appearance of wave patterns, combining elements to integrative activity by conditioning. Low-frequency oscillations of neuronal assemblies within range of 0.02-0.8 Hz act as operant processing in mechanisms of system plasticity and conditioning. |